The simplest strategy would be to put the guy on his ass at the line of scrimmage. Line up a linebacker against him and he'd never get upfield.

The other issue is this: wouldn't he outrun the QB's arm? There's a certain point at which the advantage gained by speed is negated because the receiver has to slow down to even have a chance at catching the ball on the run...and there are already plenty of receivers who are at that point. He might just be too fast to be effective.